Developments In Psychopharmacology

Developments In Psychopharmacology

by S.K.Kulkarni
 
  • ISBN: 8189304313
  • Binding: Hardbound
  • Year: 2007
  • Language: ENGLISH
PRICE:  US $ 80.00
Add to cart
 
 

Psychoneuropharmacological research has received special attention during the last four decades particularly after the discovery of Psychotropic drugs, chlorpromazine and reserpine. These drugs have not only helped in alleviating many mental disorders but also have helped neuroscientists to look deeply into the neurotransmitter based pathophysiology of the mental diseases. Of the many neurotransmitters which are involved in the behavioral effects of drugs, gamma amino butyric acid (GABA) and dopamine have received a great attention. Gamma amino butyric acid, the major inhibitory neurotransmitter ubiquitously distributed in the central nervous system modulates many neurodegenerative diseases such as epilepsy, memory deficits, stress and anxiety. The book is based on the research work conducted by the author in these areas, interestingly all these research papers emanating from the work that have been published in one single journal namely, IJEB. The author has written about the current developments in GABA receptor pharmacology and behavioral disorders and these articles are supported by selected publications from IJEB which are put in the form of book format for easy reference. Another hot area in psychopharmacology is the study of pain and pain related disorders. Again the book carries selected articles on pain and inflammation published by the author in IJEB. The book is unique in its format as it carries four important conceptual articles supported by as many as 28 of his own research articles from IJEB which makes the reader not only easy to follow but actually helps him/her in knowing the details of the experimental protocols as the research papers are also incorporated. The book is a valuable addition for postgraduate and doctoral researchers in Psychobiology, Physiology, Pharmacology and related basic medical sciences.

Dr. S.K. Kulkarni, M. Pharm., Ph.D, FAMS, FNASc, FPAS, FIPA, Professor of Pharmacology and Coordinator, UGC Centre for Potential in Biomedical Sciences of Panjab University has more than three decades of teaching and research experience. A recipient of several national recognitions for his contributions to pharmacology research and pharmaceutical sciences, he has deep insight into Experimental Pharmacology and innovations in developing simple animal models and procedures for testing of drugs in experimental animals. The book on “Developments in Psychopharmacology” is a testimony of his contributions to experimental biomedical sciences. Dr. Kulkarni is a Fellow of National Academy of Medical Sciences, National Academy of Sciences and Indian Pharmaceutical Association. He was the General President of the Indian Pharmaceutical Congress Association. He serves on many committees of the National Statutory bodies such as UGC, AICTE and CSIR systems. He was earlier Dean and Chairman of the Faculty of Pharmaceutical Sciences and Director (Hon.), Centre for Industry Institute Partnership Programme of the Panjab University and also Advisor, Sun Pharma Advanced Research Centre at Baroda.

  • Amino butyric acid receptor pharmacology: From concepts to application
  • Amino butyric acid (GABA) mediated behavioral studies
  • On the GABAergic actions of Withania somnifera: An Indian Ginseng
  • Effect of cyclooxygenase-2 (COX-2) inhibitors in various animal models (bicuculline, picrotoxin, maximal electroshock-induced convulsions) of epilepsy with possible mechanism of action
  • Motor and electrographic response of refractory experimental status epilepticus in rats and effect of calcium channel blockers
  • Studies on anticonvulsant actions of L-deprenyl
  • Pentylenetetrazol-induced kindling in animals: Protective effect of BR-16A
  • Altered response to GABAergic agents following electro and chemo convulsions in mice
  • Effect of chronic treatment of Ro 15-1788 and its withdrawal on cortical and hippocampal EEG activity in rats
  • Benzodiazepine inverse agonist, DMCM- and peripheral agonist, Ro 5-4864-induced convulsions in mice: Effect of adenosinergic agents
  • Effect of NMDA-receptor ligands on neocortical and hippocampal EEG activity of rat brain.
  • On the convulsant action of DMCM and Ro 5-4864 in Mice
  • Autonomic hyperactivity on diazepam withdrawal in rats
  • Central nervous system depressant activities of melatonin in rats and mice
  • Reversal of diazepam withdrawal induced hyperactivity in mice by BR 16-A (Mentat®), a herbal preparation
  • Protective effect of BR-16A (Mentat®), a herbal preparation on alcohol abstinence-induced anxiety and convulsions
  • Alprazolam modifies animal behaviour on elevated plus-maze
  • Prevention of development of tolerance and dependence to opiate in mice by BR-16A (Mentat®), a herbal psychotropic preparation
  • Effe ct of a herbal psyc hotro pic pr epa-ration, BR-16A (Mentat), on performance of mice on elevated plus-maze
  • Effect of reserpine, chlorp roma zine and meprobamate on stress induced metabolic alterations in urinary excretion of 3-Methoxy-4-Hydroxymandelic acid
  • Basic mechanisms of pain and inflammation: Regulators and their inhibitors
  • Potentiation of antinociceptive effect of NSAIDs by a specific lipooxygenase inhibitor, acetyl-11-keto-beta boswellic acid
  • Role of cyclooxygenase-2 in lipopolysaccharide-induced hyperalgesia in formalin test
  • Effect of licofelone against NSAIDs-induced gastrointestinal ulceration and inflammation
  • Possible analgesic and anti-inflammatory interactions of aspartame with opioids and NSAIDs
  • Cholinergic-NO-cGMP mediation of sildenafil-induced antinociception
  • Effect of 5-lipoxygenase inhibition on events associated with inflammatory bowel disease in rats
  • D2 -dopamine receptor and ?2 -adrenoreceptor-mediated analgesic response of quercetin
  • Antinociceptive action of FK506 in mice
  • Analgesic and anti-inflammatory effects of phosphodiesterase inhibitors
  • Involvement of dopamine D2 and 5-HT1A receptors in roxindole-induced antinociception
  • Antinocicepti ve effect of sumatriptan in mice
  • Index